Tryptophan metabolism promotes immune evasion in human pancreatic β cells

BACKGROUND: To resist the autoimmune attack characteristic of type 1 diabetes, insulin producing pancreatic β cells need to evade T-cell recognition. Such escape mechanisms may be conferred by low HLA class I (HLA-I) expression and upregulation of immune inhibitory molecules such as Programmed cell...

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Detalles Bibliográficos
Autores principales: Rachdi, Latif, Zhou, Zhicheng, Berthault, Claire, Lourenço, Chloe, Fouque, Alexis, Domet, Thomas, Armanet, Mathieu, You, Sylvaine, Peakman, Mark, Mallone, Roberto, Scharfmann, Raphael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10412781/
https://www.ncbi.nlm.nih.gov/pubmed/37536063
http://dx.doi.org/10.1016/j.ebiom.2023.104740

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10412781/
https://www.ncbi.nlm.nih.gov/pubmed/37536063
http://dx.doi.org/10.1016/j.ebiom.2023.104740

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