Caspase-4 dimerisation and D289 auto-processing elicit an interleukin-1β-converting enzyme

The noncanonical inflammasome is a signalling complex critical for cell defence against cytosolic Gram-negative bacteria. A key step in the human noncanonical inflammasome pathway involves unleashing the proteolytic activity of caspase-4 within this complex. Caspase-4 induces inflammatory responses...

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Detalles Bibliográficos
Autores principales: Chan, Amy H, Burgener, Sabrina S, Vezyrgiannis, Kassandra, Wang, Xiaohui, Acklam, Jadie, Von Pein, Jessica B, Pizzuto, Malvina, Labzin, Larisa I, Boucher, Dave, Schroder, Kate
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10412805/
https://www.ncbi.nlm.nih.gov/pubmed/37558421
http://dx.doi.org/10.26508/lsa.202301908

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10412805/
https://www.ncbi.nlm.nih.gov/pubmed/37558421
http://dx.doi.org/10.26508/lsa.202301908

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