High-resolution kinetic characterization of the RIG-I-signaling pathway and the antiviral response

RIG-I recognizes viral dsRNA and activates a cell-autonomous antiviral response. Upon stimulation, it triggers a signaling cascade leading to the production of type I and III IFNs. IFNs are secreted and signal to elicit the expression of IFN-stimulated genes, establishing an antiviral state of the c...

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Detalles Bibliográficos
Autores principales: Burkart, Sandy S, Schweinoch, Darius, Frankish, Jamie, Sparn, Carola, Wüst, Sandra, Urban, Christian, Merlo, Marta, Magalhães, Vladimir G, Piras, Antonio, Pichlmair, Andreas, Willemsen, Joschka, Kaderali, Lars, Binder, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10412806/
https://www.ncbi.nlm.nih.gov/pubmed/37558422
http://dx.doi.org/10.26508/lsa.202302059

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10412806/
https://www.ncbi.nlm.nih.gov/pubmed/37558422
http://dx.doi.org/10.26508/lsa.202302059

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