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High-resolution kinetic characterization of the RIG-I-signaling pathway and the antiviral response
RIG-I recognizes viral dsRNA and activates a cell-autonomous antiviral response. Upon stimulation, it triggers a signaling cascade leading to the production of type I and III IFNs. IFNs are secreted and signal to elicit the expression of IFN-stimulated genes, establishing an antiviral state of the c...
Autores principales: | Burkart, Sandy S, Schweinoch, Darius, Frankish, Jamie, Sparn, Carola, Wüst, Sandra, Urban, Christian, Merlo, Marta, Magalhães, Vladimir G, Piras, Antonio, Pichlmair, Andreas, Willemsen, Joschka, Kaderali, Lars, Binder, Marco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10412806/ https://www.ncbi.nlm.nih.gov/pubmed/37558422 http://dx.doi.org/10.26508/lsa.202302059 |
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