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Effects of short-chain per- and polyfluoroalkyl substances (PFAS) on human cytochrome P450 (CYP450) enzymes and human hepatocytes: An in vitro study
Short-chain per- and polyfluoroalkyl substances (PFAS) have been developed as alternatives to legacy long-chain PFAS, but they may still pose risks due to their potential to interact with biomolecules. Cytochrome P450 (CYP450) enzymes are essential for xenobiotic metabolism, and disruptions of these...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Elsevier
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10412865/ https://www.ncbi.nlm.nih.gov/pubmed/37575337 http://dx.doi.org/10.1016/j.crtox.2023.100116 |