Pretreatment with tadalafil attenuates cardiotoxicity induced by combretastatin A4 disodium phosphate in rats

Combretastatin A4 disodium phosphate (CA4DP) is a prodrug of combretastatin A4 (CA4), a microtubule-disassembling agent that exhibits antitumor effects by inhibiting tumor cell proliferation and inducing morphological changes and apoptosis in vascular endothelial cells in tumors. However, cardiotoxi...

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Detalles Bibliográficos
Autores principales: Nagashima, Yoshiyasu, Tochinai, Ryota, Sekizawa, Shin-ichi, Kato, Daiki, Nakagawa, Takayuki, Tsuru, Yoshiharu, Tatewaki, Yasuko, Mutoh, Tatsushi, Taki, Yasuyuki, Kuwahara, Masayoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society of Toxicologic Pathology 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10412959/
https://www.ncbi.nlm.nih.gov/pubmed/37577366
http://dx.doi.org/10.1293/tox.2022-0143

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10412959/
https://www.ncbi.nlm.nih.gov/pubmed/37577366
http://dx.doi.org/10.1293/tox.2022-0143

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