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Targeted genome mining for microbial antitumor agents acting through DNA intercalation

Microbial natural products have been one of the most important sources for drug development. In the current postgenomic era, sequence-driven approaches for natural product discovery are becoming increasingly popular. Here, we develop an effective genome mining strategy for the targeted discovery of...

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Detalles Bibliográficos
Autores principales: Zhao, Zhijie, Zhao, Guiyun, Chai, Yi, Li, Wei, Song, Kaihui, Zhao, Wenbin, Li, Hairong, Wu, Miaolian, Zhou, Zhan, Du, Yi-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10413001/
https://www.ncbi.nlm.nih.gov/pubmed/37575356
http://dx.doi.org/10.1016/j.synbio.2023.07.003