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Targeted genome mining for microbial antitumor agents acting through DNA intercalation
Microbial natural products have been one of the most important sources for drug development. In the current postgenomic era, sequence-driven approaches for natural product discovery are becoming increasingly popular. Here, we develop an effective genome mining strategy for the targeted discovery of...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
KeAi Publishing
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10413001/ https://www.ncbi.nlm.nih.gov/pubmed/37575356 http://dx.doi.org/10.1016/j.synbio.2023.07.003 |