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EGFR exon 20 insertion mutations and ERBB2 mutations in lung cancer: a narrative review on approved targeted therapies from oral kinase inhibitors to antibody-drug conjugates

BACKGROUND AND OBJECTIVE: This review will provide an overview of EGFR and ERBB2 mutations in non-small-cell lung cancer (NSCLC) with a focus on recent clinical approvals. METHODS: We obtained data from the literature in accordance with narrative review reporting guidelines. KEY CONTENT AND FINDINGS...

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Detalles Bibliográficos
Autores principales: Sentana-Lledo, Daniel, Academia, Emmeline, Viray, Hollis, Rangachari, Deepa, Kobayashi, Susumu S., VanderLaan, Paul A., Costa, Daniel B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10413034/
https://www.ncbi.nlm.nih.gov/pubmed/37577308
http://dx.doi.org/10.21037/tlcr-23-98