Detection of resistance mutations in patients with anaplastic lymphoma kinase-rearranged lung cancer through liquid biopsy

BACKGROUND: Tyrosine kinase inhibitors (TKIs) significantly improve clinical outcomes in patients with non-small cell lung cancer due to anaplastic lymphoma kinase (ALK) gene rearrangement. However, the rate of relapse with TKIs is high owing to the development of resistance mutations during treatme...

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Detalles Bibliográficos
Autores principales: Sasaki, Takaaki, Yoshida, Ryohei, Nitanai, Kiichi, Watanabe, Takashi, Tenma, Toshiyuki, Kida, Ryotaro, Mori, Chie, Umekage, Yasuhiro, Hirai, Noriko, Minami, Yoshinori, Okumura, Shunsuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10413038/
https://www.ncbi.nlm.nih.gov/pubmed/37577301
http://dx.doi.org/10.21037/tlcr-22-671

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10413038/
https://www.ncbi.nlm.nih.gov/pubmed/37577301
http://dx.doi.org/10.21037/tlcr-22-671

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