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Detection of resistance mutations in patients with anaplastic lymphoma kinase-rearranged lung cancer through liquid biopsy
BACKGROUND: Tyrosine kinase inhibitors (TKIs) significantly improve clinical outcomes in patients with non-small cell lung cancer due to anaplastic lymphoma kinase (ALK) gene rearrangement. However, the rate of relapse with TKIs is high owing to the development of resistance mutations during treatme...
Autores principales: | Sasaki, Takaaki, Yoshida, Ryohei, Nitanai, Kiichi, Watanabe, Takashi, Tenma, Toshiyuki, Kida, Ryotaro, Mori, Chie, Umekage, Yasuhiro, Hirai, Noriko, Minami, Yoshinori, Okumura, Shunsuke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10413038/ https://www.ncbi.nlm.nih.gov/pubmed/37577301 http://dx.doi.org/10.21037/tlcr-22-671 |
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