Synthetic receptor platform to identify loss-of-function single nucleotide variants and designed mutants in the death receptor Fas/CD95

Synthetic biology has emerged as a useful technology for studying cytokine signal transduction. Recently, we described fully synthetic cytokine receptors to phenocopy trimeric receptors such as the death receptor Fas/CD95. Using a nanobody as an extracellular-binding domain for mCherry fused to the...

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Detalles Bibliográficos
Autores principales: Minafra, Anna Rita, Rafii, Puyan, Mossner, Sofie, Bazgir, Farhad, Floss, Doreen M., Moll, Jens M., Scheller, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10413154/
https://www.ncbi.nlm.nih.gov/pubmed/37392849
http://dx.doi.org/10.1016/j.jbc.2023.104989

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10413154/
https://www.ncbi.nlm.nih.gov/pubmed/37392849
http://dx.doi.org/10.1016/j.jbc.2023.104989

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