In-Depth Specificity Profiling of Endopeptidases Using Dedicated Mix-and-Split Synthetic Peptide Libraries and Mass Spectrometry

[Image: see text] Proteases comprise the class of enzymes that catalyzes the hydrolysis of peptide bonds, thereby playing a pivotal role in many aspects of life. The amino acids surrounding the scissile bond determine the susceptibility toward protease-mediated hydrolysis. A detailed understanding o...

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Detalles Bibliográficos
Autores principales: Claushuis, Bart, Cordfunke, Robert A., de Ru, Arnoud H., Otte, Annemarie, van Leeuwen, Hans C., Klychnikov, Oleg I., van Veelen, Peter A., Corver, Jeroen, Drijfhout, Jan W., Hensbergen, Paul J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10413326/
https://www.ncbi.nlm.nih.gov/pubmed/37495545
http://dx.doi.org/10.1021/acs.analchem.3c01215

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10413326/
https://www.ncbi.nlm.nih.gov/pubmed/37495545
http://dx.doi.org/10.1021/acs.analchem.3c01215

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