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Mitochondrial cytochrome P450 1B1 is involved in pregnenolone synthesis in human brain cells
Neurosteroids, which are steroids synthesized by the nervous system, can exert neuromodulatory and neuroprotective effects via genomic and nongenomic pathways. The neurosteroid and major steroid precursor pregnenolone has therapeutical potential in various diseases, such as psychiatric and pain diso...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10413356/ https://www.ncbi.nlm.nih.gov/pubmed/37442234 http://dx.doi.org/10.1016/j.jbc.2023.105035 |