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Accelerated export of Dicer1 from lipid-challenged hepatocytes buffers cellular miRNA-122 levels and prevents cell death

Hepatocytes on exposure to high levels of lipids reorganize the metabolic program while fighting against the toxicity associated with elevated cellular lipids. The mechanism of this metabolic reorientation and stress management in lipid-challenged hepatocytes has not been well explored. We have note...

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Detalles Bibliográficos
Autores principales: Bandyopadhyay, Diptankar, Basu, Sudarshana, Mukherjee, Ishita, Chakrabarti, Saikat, Chakrabarti, Partha, Mukherjee, Kamalika, Bhattacharyya, Suvendra N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10413358/
https://www.ncbi.nlm.nih.gov/pubmed/37394005
http://dx.doi.org/10.1016/j.jbc.2023.104999