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On the basis of sex: male vs. female rat adenosine A(1)/A(2A) receptor affinity

OBJECTIVE: To ensure reproducibility in biomedical research, the biological variable sex must be reported; yet a reason for using male (instead of female) rodents is seldom given. In our search for novel adenosine receptor ligands, our research group routinely determines a test compound’s binding af...

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Detalles Bibliográficos
Autores principales: Janse van Rensburg, Helena D., Terre’Blanche, Gisella, Van der Walt, Mietha M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10413537/
https://www.ncbi.nlm.nih.gov/pubmed/37563689
http://dx.doi.org/10.1186/s13104-023-06346-7