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Signatures of disease progression in knee osteoarthritis: insights from an integrated multi-scale modeling approach, a proof of concept

Introduction: Knee osteoarthritis (KOA) is characterized by articular cartilage degeneration. It has been widely accepted that the mechanical joint environment plays a significant role in the onset and progression of this disease. In silico models have been used to study the interplay between mechan...

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Detalles Bibliográficos
Autores principales: Mohout, Ikram, Elahi, Seyed Ali, Esrafilian, Amir, Killen, Bryce A., Korhonen, Rami K., Verschueren, Sabine, Jonkers, Ilse
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10413555/
https://www.ncbi.nlm.nih.gov/pubmed/37576991
http://dx.doi.org/10.3389/fbioe.2023.1214693