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Automated time-lapse data segmentation reveals in vivo cell state dynamics

Embryonic development proceeds as a series of orderly cell state transitions built upon noisy molecular processes. We defined gene expression and cell motion states using single-cell RNA sequencing data and in vivo time-lapse cell tracking data of the zebrafish tailbud. We performed a parallel ident...

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Detalles Bibliográficos
Autores principales: Genuth, Miriam A., Kojima, Yasuhiro, Jülich, Dörthe, Kiryu, Hisanori, Holley, Scott A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10413672/
https://www.ncbi.nlm.nih.gov/pubmed/37267354
http://dx.doi.org/10.1126/sciadv.adf1814