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An AAV-CRISPR/Cas9 strategy for gene editing across divergent rodent species: Targeting neural oxytocin receptors as a proof of concept

A major issue in neuroscience is the poor translatability of research results from preclinical studies in animals to clinical outcomes. Comparative neuroscience can overcome this barrier by studying multiple species to differentiate between species-specific and general mechanisms of neural circuit f...

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Detalles Bibliográficos
Autores principales: Boender, Arjen J., Boon, Marina, Albers, H. Elliott, Eck, Samantha R., Fricker, Brandon A., Kelly, Aubrey M., LeDoux, Joseph E., Motta, Simone C., Shrestha, Prerana, Taylor, Jack H., Trainor, Brian C., Triana-Del Rio, Rodrigo, Young, Larry J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10413677/
https://www.ncbi.nlm.nih.gov/pubmed/37256960
http://dx.doi.org/10.1126/sciadv.adf4950