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The deubiquitinase EIF3H promotes hepatocellular carcinoma progression by stabilizing OGT and inhibiting ferroptosis

Hepatocellular carcinoma (HCC) is one of the most prevalent and lethal human malignancies, and with quite limited treatment alternatives. The proteasome is responsible for most of the protein degradation in eukaryotic cells and required for the maintenance of intracellular homeostasis. However, its...

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Detalles Bibliográficos
Autores principales: Tang, Jianing, Long, Guo, Li, Xuanxuan, Zhou, Ledu, Zhou, Yangying, Wu, Zheyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10413709/
https://www.ncbi.nlm.nih.gov/pubmed/37559097
http://dx.doi.org/10.1186/s12964-023-01220-2