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SNP rs11185644 in RXRA gene and SNP rs2235544 in DIO1 gene predict dosage requirements in a cross-sectional sample of hypothyroid patients

BACKGROUND AND PURPOSE: Primary hypothyroidism due to abnormality in the thyroid gland is the most common endocrine disease The recommended starting dose of levothyroxine replacement therapy is 1.6 µg/kg. This dose however is not optimal for every patient and dose adjustments are frequently done. Ge...

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Detalles Bibliográficos
Autores principales: AlEjielat, Rowan, Khaleel, Anas, Batarseh, Yazan S., Abu-Qatouseh, Luay, Al-Wawi, Suzan, AlSunna, Toleen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10413766/
https://www.ncbi.nlm.nih.gov/pubmed/37563580
http://dx.doi.org/10.1186/s12902-023-01425-z