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IL-1β Derived Th17 Immune Responses Are a Critical Factor for Neutrophilic-Eosinophilic Airway Inflammation on Psychological Stress-Induced Immune Tolerance Breakdown in Mice

INTRODUCTION: Asthma is an inflammatory reaction mediated by type 2 helper T (Th2) cells and is known to increase eosinophil levels. Our previous study showed that stress-related asthma can cause neutrophilic and eosinophilic airway inflammation by suppressing immune tolerance. However, the mechanis...

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Detalles Bibliográficos
Autores principales: Sato, Shinsuke, Kawano, Tasuku, Ike, Erina, Takahashi, Kento, Sakurai, Junji, Miyasaka, Tomomitsu, Miyauchi, Yasuo, Ishizawa, Fumiaki, Takayanagi, Motoaki, Takahashi, Tomoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10413803/
https://www.ncbi.nlm.nih.gov/pubmed/37231861
http://dx.doi.org/10.1159/000529108