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P176S Mutation Rewires Electrostatic Interactions That Alter Maspin Functionality

[Image: see text] Maspin is known to regress tumors by inhibiting angiogenesis; however, its roles have been reported to be context- and sequence-dependent. Various proteins and cofactors bind to maspin, possibly explaining its conflicting roles. Moreover, polymorphic forms of maspin have also been...

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Detalles Bibliográficos
Autores principales: Anwar, Muhammad Ayaz, Haseeb, Muhammad, Choi, Sangdun, Kim, Kwang Pyo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10413834/
https://www.ncbi.nlm.nih.gov/pubmed/37576651
http://dx.doi.org/10.1021/acsomega.3c01850