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P176S Mutation Rewires Electrostatic Interactions That Alter Maspin Functionality
[Image: see text] Maspin is known to regress tumors by inhibiting angiogenesis; however, its roles have been reported to be context- and sequence-dependent. Various proteins and cofactors bind to maspin, possibly explaining its conflicting roles. Moreover, polymorphic forms of maspin have also been...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10413834/ https://www.ncbi.nlm.nih.gov/pubmed/37576651 http://dx.doi.org/10.1021/acsomega.3c01850 |