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Exploration of Thiourea-Based Scaffolds for the Construction of Bacterial Ureases Inhibitors
[Image: see text] A series of 32 thiourea-based urease inhibitors were synthesized and evaluated against native bacterial enzyme and whole cells of Sporosarcina pasteurii and Proteus mirabilis strains. The proposed inhibitors represented structurally diverse thiosemicarbazones and thiocarbohydrazone...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10413841/ https://www.ncbi.nlm.nih.gov/pubmed/37576686 http://dx.doi.org/10.1021/acsomega.3c03702 |