Cargando…

Exploration of Thiourea-Based Scaffolds for the Construction of Bacterial Ureases Inhibitors

[Image: see text] A series of 32 thiourea-based urease inhibitors were synthesized and evaluated against native bacterial enzyme and whole cells of Sporosarcina pasteurii and Proteus mirabilis strains. The proposed inhibitors represented structurally diverse thiosemicarbazones and thiocarbohydrazone...

Descripción completa

Detalles Bibliográficos
Autores principales: Tabor, Wojciech, Katsogiannou, Aikaterini, Karta, Danai, Andrianopoulou, Evgenia, Berlicki, Łukasz, Vassiliou, Stamatia, Grabowiecka, Agnieszka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10413841/
https://www.ncbi.nlm.nih.gov/pubmed/37576686
http://dx.doi.org/10.1021/acsomega.3c03702