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Exploration of Thiourea-Based Scaffolds for the Construction of Bacterial Ureases Inhibitors

[Image: see text] A series of 32 thiourea-based urease inhibitors were synthesized and evaluated against native bacterial enzyme and whole cells of Sporosarcina pasteurii and Proteus mirabilis strains. The proposed inhibitors represented structurally diverse thiosemicarbazones and thiocarbohydrazone...

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Detalles Bibliográficos
Autores principales:	Tabor, Wojciech, Katsogiannou, Aikaterini, Karta, Danai, Andrianopoulou, Evgenia, Berlicki, Łukasz, Vassiliou, Stamatia, Grabowiecka, Agnieszka
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2023
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10413841/ https://www.ncbi.nlm.nih.gov/pubmed/37576686 http://dx.doi.org/10.1021/acsomega.3c03702

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