Structure and Function of RhoBTB1 Required for Substrate Specificity and Cullin-3 Ubiquitination

We identified Rho-related BTB domain containing 1 (RhoBTB1) as a key regulator of phosphodiesterase 5 (PDE5) activity, and through PDE5, a regulator of vascular tone. We identified the binding interface for PDE5 on RhoBTB1 by truncating full-length RhoBTB1 into its component domains. Co-immunoprecip...

Descripción completa

Detalles Bibliográficos
Autores principales: Kumar, Gaurav, Fang, Shi, Golosova, Daria, Lu, Ko-Ting, Brozoski, Daniel T, Vazirabad, Ibrahim, Sigmund, Curt D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10413933/
https://www.ncbi.nlm.nih.gov/pubmed/37575477
http://dx.doi.org/10.1093/function/zqad034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10413933/
https://www.ncbi.nlm.nih.gov/pubmed/37575477
http://dx.doi.org/10.1093/function/zqad034

Ejemplares similares