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AF9 sustains glycolysis in colorectal cancer via H3K9ac‐mediated PCK2 and FBP1 transcription

BACKGROUND: The tumourigenesis of various cancers is influenced by epigenetic deregulation. Among 591 epigenetic regulator factors (ERFs) examined, AF9 showed significant inhibition of malignancy in colorectal cancer (CRC) based on our wound healing assays. However, the precise role of AF9 in CRC re...

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Detalles Bibliográficos
Autores principales: He, Xuefeng, Zhong, Xinyang, Fang, Yi, Hu, Zijuan, Chen, Zhiyu, Wang, Yaxian, Huang, Huixia, Zhao, Senlin, Li, Dawei, Wei, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10413954/
https://www.ncbi.nlm.nih.gov/pubmed/37565737
http://dx.doi.org/10.1002/ctm2.1352