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The fate of extra centrosomes in newly formed tetraploid cells: should I stay, or should I go?

An increase in centrosome number is commonly observed in cancer cells, but the role centrosome amplification plays along with how and when it occurs during cancer development is unclear. One mechanism for generating cancer cells with extra centrosomes is whole genome doubling (WGD), an event that oc...

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Detalles Bibliográficos
Autores principales: Bloomfield, Mathew, Cimini, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10413984/
https://www.ncbi.nlm.nih.gov/pubmed/37576603
http://dx.doi.org/10.3389/fcell.2023.1210983