Hemoglobin and cerebral hypoxic vasodilation in humans: Evidence for nitric oxide-dependent and S-nitrosothiol mediated signal transduction

Cerebral hypoxic vasodilation is poorly understood in humans, which undermines the development of therapeutics to optimize cerebral oxygen delivery. Across four investigations (total n = 195) we investigated the role of nitric oxide (NO) and hemoglobin-based S-nitrosothiol (RSNO) and nitrite ( [Form...

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Detalles Bibliográficos
Autores principales: Hoiland, Ryan L, MacLeod, David B, Stacey, Benjamin S, Caldwell, Hannah G, Howe, Connor A, Nowak-Flück, Daniela, Carr, Jay MJR, Tymko, Michael M, Coombs, Geoff B, Patrician, Alexander, Tremblay, Joshua C, Van Mierlo, Michelle, Gasho, Chris, Stembridge, Mike, Sekhon, Mypinder S, Bailey, Damian M, Ainslie, Philip N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10414015/
https://www.ncbi.nlm.nih.gov/pubmed/37042194
http://dx.doi.org/10.1177/0271678X231169579

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10414015/
https://www.ncbi.nlm.nih.gov/pubmed/37042194
http://dx.doi.org/10.1177/0271678X231169579

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