Effects of Cathepsin S Inhibition in the Age-Related Dry Eye Phenotype

PURPOSE: Aged C57BL/6J (B6) mice have increased levels of cathepsin S, and aged cathepsin S (Ctss(−)(/)(−)) knockout mice are resistant to age-related dry eye. This study investigated the effects of cathepsin S inhibition on age-related dry eye disease. METHODS: Female B6 mice aged 15.5 to 17 months...

Descripción completa

Detalles Bibliográficos
Autores principales: Galletti, Jeremias G., Scholand, Kaitlin K., Trujillo-Vargas, Claudia M., Haap, Wolfgang, Santos-Ferreira, Tiago, Ullmer, Christoph, Yu, Zhiyuan, de Paiva, Cintia S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2023
Materias:
Anatomy and Pathology/Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10414132/
https://www.ncbi.nlm.nih.gov/pubmed/37540176
http://dx.doi.org/10.1167/iovs.64.11.7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10414132/
https://www.ncbi.nlm.nih.gov/pubmed/37540176
http://dx.doi.org/10.1167/iovs.64.11.7

Ejemplares similares