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Effects of Cathepsin S Inhibition in the Age-Related Dry Eye Phenotype

PURPOSE: Aged C57BL/6J (B6) mice have increased levels of cathepsin S, and aged cathepsin S (Ctss(−)(/)(−)) knockout mice are resistant to age-related dry eye. This study investigated the effects of cathepsin S inhibition on age-related dry eye disease. METHODS: Female B6 mice aged 15.5 to 17 months...

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Detalles Bibliográficos
Autores principales:	Galletti, Jeremias G., Scholand, Kaitlin K., Trujillo-Vargas, Claudia M., Haap, Wolfgang, Santos-Ferreira, Tiago, Ullmer, Christoph, Yu, Zhiyuan, de Paiva, Cintia S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2023
Materias:	Anatomy and Pathology/Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10414132/ https://www.ncbi.nlm.nih.gov/pubmed/37540176 http://dx.doi.org/10.1167/iovs.64.11.7

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