DNA methyltransferase inhibitor 5-azacytidine enhances neuroblastoma cell lysis by an oncolytic parainfluenza virus

Studies with neuroblastoma have shown that the presence of aberrant DNA epigenetic modifications mediated by DNA methyltransferases correlates with poor prognosis, making these enzymes a target for therapeutics based on synthetic epigenetic modulators such as DNA methyltransferase inhibitors (DNMTi)...

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Detalles Bibliográficos
Autores principales: Kedarinath, Kritika, Shiffer, Elisabeth M., Parks, Griffith D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Clinical Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10414160/
https://www.ncbi.nlm.nih.gov/pubmed/37227036
http://dx.doi.org/10.1097/CAD.0000000000001525

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10414160/
https://www.ncbi.nlm.nih.gov/pubmed/37227036
http://dx.doi.org/10.1097/CAD.0000000000001525

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