Selection of the Optimal L-asparaginase II Against Acute Lymphoblastic Leukemia: An In Silico Approach

BACKGROUND: L-asparaginase II (asnB), a periplasmic protein commercially extracted from E coli and Erwinia, is often used to treat acute lymphoblastic leukemia. L-asparaginase is an enzyme that converts L-asparagine to aspartic acid and ammonia. Cancer cells are dependent on asparagine from other so...

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Detalles Bibliográficos
Autores principales: Baral, Adesh, Gorkhali, Ritesh, Basnet, Amit, Koirala, Shubham, Bhattarai, Hitesh Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JMIR Publications 2021
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10414282/
https://www.ncbi.nlm.nih.gov/pubmed/37725538
http://dx.doi.org/10.2196/29844

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10414282/
https://www.ncbi.nlm.nih.gov/pubmed/37725538
http://dx.doi.org/10.2196/29844

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