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Selection of the Optimal L-asparaginase II Against Acute Lymphoblastic Leukemia: An In Silico Approach
BACKGROUND: L-asparaginase II (asnB), a periplasmic protein commercially extracted from E coli and Erwinia, is often used to treat acute lymphoblastic leukemia. L-asparaginase is an enzyme that converts L-asparagine to aspartic acid and ammonia. Cancer cells are dependent on asparagine from other so...
Autores principales: | Baral, Adesh, Gorkhali, Ritesh, Basnet, Amit, Koirala, Shubham, Bhattarai, Hitesh Kumar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
JMIR Publications
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10414282/ https://www.ncbi.nlm.nih.gov/pubmed/37725538 http://dx.doi.org/10.2196/29844 |
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