A statistical framework to identify cell types whose genetically regulated proportions are associated with complex diseases

Finding disease-relevant tissues and cell types can facilitate the identification and investigation of functional genes and variants. In particular, cell type proportions can serve as potential disease predictive biomarkers. In this manuscript, we introduce a novel statistical framework, cell-type W...

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Detalles Bibliográficos
Autores principales: Liu, Wei, Deng, Wenxuan, Chen, Ming, Dong, Zihan, Zhu, Biqing, Yu, Zhaolong, Tang, Daiwei, Sauler, Maor, Lin, Chen, Wain, Louise V., Cho, Michael H., Kaminski, Naftali, Zhao, Hongyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Methods
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10414598/
https://www.ncbi.nlm.nih.gov/pubmed/37523391
http://dx.doi.org/10.1371/journal.pgen.1010825

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10414598/
https://www.ncbi.nlm.nih.gov/pubmed/37523391
http://dx.doi.org/10.1371/journal.pgen.1010825

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