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High-Grade Serous Carcinoma at Risk-Reducing Salpingo-Oophorectomy in Asymptomatic Carriers of BRCA1/2 Pathogenic Variants: Prevalence and Clinical Factors

To investigate the prevalence of and clinical factors associated with high-grade serous carcinoma (HGSC) at risk-reducing salpingo-oophorectomy (RRSO) in asymptomatic BRCA1/2-pathogenic variant (PV) carriers. PATIENTS AND METHODS: We included BRCA1/2-PV carriers who underwent RRSO between 1995 and 2...

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Detalles Bibliográficos
Autores principales: Stroot, Iris A.S., Brouwer, Jan, Bart, Joost, Hollema, Harry, Stommel-Jenner, Denise J., Wagner, Marise M., van Doorn, Helena C., de Hullu, Joanne A., Gaarenstroom, Katja N., Beurden, Marc, van Lonkhuijzen, Luc R.C.W., Slangen, Brigitte F.M., Zweemer, Ronald P., Gómez Garcia, Encarna B., Ausems, Margreet G.E.M., Boere, Ingrid A., van Engelen, Klaartje, van Asperen, Christi J., Schmidt, Marjanka K., Wevers, Marijke R., de Bock, Geertruida H., Mourits, Marian J.E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10414703/
https://www.ncbi.nlm.nih.gov/pubmed/36809028
http://dx.doi.org/10.1200/JCO.22.01237