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Hormone replacement therapy for postmenopausal atherosclerosis is offset by late age iron deposition

Postmenopausal atherosclerosis (AS) has been attributed to estrogen deficiency. However, the beneficial effect of hormone replacement therapy (HRT) is lost in late postmenopausal women with atherogenesis. We asked whether aging-related iron accumulation affects estrogen receptor α (ERα) expression,...

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Detalles Bibliográficos
Autores principales: Xu, Tianze, Cai, Jing, Wang, Lei, Xu, Li, Zhao, Hongting, Wang, Fudi, Meyron-Holtz, Esther G, Missirlis, Fanis, Qiao, Tong, Li, Kuanyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10414966/
https://www.ncbi.nlm.nih.gov/pubmed/37561022
http://dx.doi.org/10.7554/eLife.80494