Divergent functional outcomes of NLRP3 blockade downstream of multi-inflammasome activation: therapeutic implications for ALS

NOD-Like Receptor Family Pyrin Domain Containing 3 (NLRP3) inflammasome modulation has emerged as a potential therapeutic approach targeting inflammation amplified by pyroptotic innate immune cell death. In diseases characterized by non-cell autonomous neurodegeneration including amyotrophic lateral...

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Detalles Bibliográficos
Autores principales: Clénet, Marie-Laure, Keaney, James, Gillet, Gaëlle, Valadas, Jorge S., Langlois, Julie, Cardenas, Alvaro, Gasser, Julien, Kadiu, Irena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10415077/
https://www.ncbi.nlm.nih.gov/pubmed/37575265
http://dx.doi.org/10.3389/fimmu.2023.1190219

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10415077/
https://www.ncbi.nlm.nih.gov/pubmed/37575265
http://dx.doi.org/10.3389/fimmu.2023.1190219

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