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Metallohelices stabilize DNA three-way junctions and induce DNA damage in cancer cells
DNA three-way junctions (3WJ) represent one of the simplest supramolecular DNA structures arising as intermediates in homologous recombination in the absence of replication. They are also formed transiently during DNA replication. Here we examine the ability of Fe(II)-based metallohelices to act as...
Autores principales: | Malina, Jaroslav, Kostrhunova, Hana, Scott, Peter, Brabec, Viktor |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10415117/ https://www.ncbi.nlm.nih.gov/pubmed/37351627 http://dx.doi.org/10.1093/nar/gkad536 |
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