Pyrimidine catabolism is required to prevent the accumulation of 5-methyluridine in RNA

5-Methylated cytosine is a frequent modification in eukaryotic RNA and DNA influencing mRNA stability and gene expression. Here we show that free 5-methylcytidine (5mC) and 5-methyl-2′-deoxycytidine are generated from nucleic acid turnover in Arabidopsis thaliana, and elucidate how these cytidines a...

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Detalles Bibliográficos
Autores principales: Gao, Shangyu, Sun, Yu, Chen, Xiaoguang, Zhu, Changhua, Liu, Xiaoye, Wang, Wenlei, Gan, Lijun, Lu, Yanwu, Schaarschmidt, Frank, Herde, Marco, Witte, Claus-Peter, Chen, Mingjia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10415118/
https://www.ncbi.nlm.nih.gov/pubmed/37334828
http://dx.doi.org/10.1093/nar/gkad529

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10415118/
https://www.ncbi.nlm.nih.gov/pubmed/37334828
http://dx.doi.org/10.1093/nar/gkad529

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