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Simultaneous multifunctional transcriptome engineering by CRISPR RNA scaffold

RNA processing and metabolism are subjected to precise regulation in the cell to ensure integrity and functions of RNA. Though targeted RNA engineering has become feasible with the discovery and engineering of the CRISPR-Cas13 system, simultaneous modulation of different RNA processing steps remains...

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Detalles Bibliográficos
Autores principales: Liu, Zukai, Jillette, Nathaniel, Robson, Paul, Cheng, Albert Wu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10415119/
https://www.ncbi.nlm.nih.gov/pubmed/37395412
http://dx.doi.org/10.1093/nar/gkad547