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Structural and biochemical insights into the molecular mechanism of TRPT1 for nucleic acid ADP-ribosylation

Nucleic acid ADP-ribosylation has been established as a novel modification found in a wide diversity of prokaryotic and eukaryotic organisms. tRNA 2′-phosphotransferase 1 (TRPT1/TPT1/KptA) possesses ADP-ribosyltransferase (ART) activity and is able to ADP-ribosylate nucleic acids. However, the under...

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Detalles Bibliográficos
Autores principales: Yang, Xiaoyun, Wang, Jiaxu, Li, Simin, Li, Xiaobing, Gong, Jingjing, Yan, Zhenzhen, Zhou, Huan, Wu, Chen, Liu, Xiuhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10415124/
https://www.ncbi.nlm.nih.gov/pubmed/37334830
http://dx.doi.org/10.1093/nar/gkad525