Structural basis for high-affinity recognition of aflatoxin B1 by a DNA aptamer

The 26-mer DNA aptamer (AF26) that specifically binds aflatoxin B1 (AFB1) with nM-level high affinity is rare among hundreds of aptamers for small molecules. Despite its predicted stem–loop structure, the molecular basis of its high-affinity recognition of AFB1 remains unknown. Here, we present the...

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Detalles Bibliográficos
Autores principales: Xu, Guohua, Wang, Chen, Yu, Hao, Li, Yapiao, Zhao, Qiang, Zhou, Xin, Li, Conggang, Liu, Maili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10415127/
https://www.ncbi.nlm.nih.gov/pubmed/37351632
http://dx.doi.org/10.1093/nar/gkad541

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10415127/
https://www.ncbi.nlm.nih.gov/pubmed/37351632
http://dx.doi.org/10.1093/nar/gkad541

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