The CSB chromatin remodeler regulates PARP1- and PARP2-mediated single-strand break repair at actively transcribed DNA regions

Efficient repair of oxidized DNA is critical for genome-integrity maintenance. Cockayne syndrome protein B (CSB) is an ATP-dependent chromatin remodeler that collaborates with Poly(ADP-ribose) polymerase I (PARP1) in the repair of oxidative DNA lesions. How these proteins integrate during DNA repair...

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Detalles Bibliográficos
Autores principales: Bilkis, Rabeya, Lake, Robert J, Cooper, Karen L, Tomkinson, Alan, Fan, Hua-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10415129/
https://www.ncbi.nlm.nih.gov/pubmed/37326017
http://dx.doi.org/10.1093/nar/gkad515

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10415129/
https://www.ncbi.nlm.nih.gov/pubmed/37326017
http://dx.doi.org/10.1093/nar/gkad515

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