Nsp14 of SARS-CoV-2 inhibits mRNA processing and nuclear export by targeting the nuclear cap-binding complex

To facilitate selfish replication, viruses halt host gene expression in various ways. The nuclear export of mRNA is one such process targeted by many viruses. SARS-CoV-2, the etiological agent of severe acute respiratory syndrome, also prevents mRNA nuclear export. In this study, Nsp14, a bifunction...

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Detalles Bibliográficos
Autores principales: Katahira, Jun, Ohmae, Tatsuya, Yasugi, Mayo, Sasaki, Ryosuke, Itoh, Yumi, Kohda, Tomoko, Hieda, Miki, Yokota Hirai, Masami, Okamoto, Toru, Miyamoto, Yoichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10415132/
https://www.ncbi.nlm.nih.gov/pubmed/37260089
http://dx.doi.org/10.1093/nar/gkad483

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10415132/
https://www.ncbi.nlm.nih.gov/pubmed/37260089
http://dx.doi.org/10.1093/nar/gkad483

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