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Divergent directed evolution of a TetR-type repressor towards aromatic molecules

Reprogramming cellular behaviour is one of the hallmarks of synthetic biology. To this end, prokaryotic allosteric transcription factors (aTF) have been repurposed as versatile tools for processing small molecule signals into cellular responses. Expanding the toolbox of aTFs that recognize new induc...

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Detalles Bibliográficos
Autores principales: Nasr, Mohamed A, Martin, Vincent J J, Kwan, David H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10415137/
https://www.ncbi.nlm.nih.gov/pubmed/37377432
http://dx.doi.org/10.1093/nar/gkad503