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Activity, substrate preference and structure of the HsMCM8/9 helicase

The minichromosomal maintenance proteins, MCM8 and MCM9, are more recent evolutionary additions to the MCM family, only cooccurring in selected higher eukaryotes. Mutations in these genes are directly linked to ovarian insufficiency, infertility, and several cancers. MCM8/9 appears to have ancillary...

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Detalles Bibliográficos
Autores principales: McKinzey, David R, Li, Chuxuan, Gao, Yang, Trakselis, Michael A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10415141/
https://www.ncbi.nlm.nih.gov/pubmed/37309874
http://dx.doi.org/10.1093/nar/gkad508