Mitochondrial protein MPV17 promotes β-cell apoptosis in diabetogenesis

MPV17 is a mitochondrial inner membrane protein, and its deficiency can cause mitochondrial DNA (mtDNA) depletion, increase reactive oxygen species (ROS), and promote apoptosis in several cell types, suggesting that MPV17 plays a protective role in cells although the underlying mechanism remains unk...

Descripción completa

Detalles Bibliográficos
Autores principales: Tang, Qiaoli, Shi, Wanting, Liu, Ming, Tang, Liqin, Ren, Wei, Shi, Shaolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2023
Materias:
Cell Death & Injury
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10415165/
https://www.ncbi.nlm.nih.gov/pubmed/37522959
http://dx.doi.org/10.1042/CS20230164

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10415165/
https://www.ncbi.nlm.nih.gov/pubmed/37522959
http://dx.doi.org/10.1042/CS20230164

Ejemplares similares