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Mitochondrial protein MPV17 promotes β-cell apoptosis in diabetogenesis
MPV17 is a mitochondrial inner membrane protein, and its deficiency can cause mitochondrial DNA (mtDNA) depletion, increase reactive oxygen species (ROS), and promote apoptosis in several cell types, suggesting that MPV17 plays a protective role in cells although the underlying mechanism remains unk...
Autores principales: | Tang, Qiaoli, Shi, Wanting, Liu, Ming, Tang, Liqin, Ren, Wei, Shi, Shaolin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10415165/ https://www.ncbi.nlm.nih.gov/pubmed/37522959 http://dx.doi.org/10.1042/CS20230164 |
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